Yuanyuan (Rose) Li

Rose Li
Assistant Professor of Obstetrics, Gynecology, and Women's Health
1 Hospital Drive, NW508

Ph.D., Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing, China, 2006

M.D., Shanxi Medical University, Taiyuan, China, 2000

Research Summary

Nutrition intervention on human diseases through epigenetic mechanisms and gut microbiome

Research Description

My research primarily focuses on nutrition intervention on human diseases utilizing mice as main animal models. Beneficial diets and bioactive phytochemicals have been found to associate with a lower incidence and mortality in a variety of human diseases. Specifically, our laboratory studies the potential mechanisms involved in these bioactive compounds on prevention of cancer, obesity and aging through epigenetic regulation of key gene expression and gut microbiome. 

As a faculty member of the Department of OB&GYN and Women’s Health, I developed a new research area in studying how maternal nutrition interferes in epigenetic reprogramming processes during early life, leading to in uteroprevention outcomes such as reduced risks of breast cancer or obesity later in offspring life.

To promote translational studies, I am interested in applying our studies to human subjects to develop novel nutritional prevention or therapeutic strategies for breast cancer as well as nutrition intervention approaches in alleviating maternal/fetal complications during pregnancy, eventually leading to improved women’s health and life quality.

Awards and Honors

Awardee of MU Tier1 Sequencing Initiative Proposal Competition, 2021

Winner of ILSI North American Research Design Challenge, 2018

Finalist of 2018 Future Leader AWard in ILSI North America

Recipient of the Mary Swartz Rose Young Investigator Award from the American Society for Nutrition, 2014

Selected Publications

See Google Scholar for a list of Dr. Li's publications.